This has been an ongoing issue with X11 compositers like marco, unity and cinnamon etc... Ifind especially with an Nvidia GPU that as the system runs longer after a number of weeks or a number of months the GUI just gets slower and slower. It's not something you'll instantly notice but just a hint of lag here or there that gets worse.
One hint you'll find is by watching nvidia-smi and checking the utilization you will start seeing random spikes of 80-100% even without maxi........
I used to believe that for Desktops especially that the "ondemand" CPUfrequency changing that kernels included with Ubuntu and Debian based distros have would be sufficient for snappy performance.
However, you can feel the lack of performance on the fastest computer if you have ondemand. A lot of times even under high load 100% of your CPUfrequency in MHz will not be used.
For example a 2.8Ghz CPUmay only run at 1.8MHz or even .9GHz. Now........