Are you or your users tired of getting support requests for the missing Visual C++ Library DLL's? Some programs prompt you to install them but the easiest way is to modify your Windows image or program to just include these already.
The easiest way is to use Microsoft's guide to copy the right architecture of DLL's and include them in your software and make sure the software adds its directory to the PATH for Windows.........
This is sure simple if you follow the guide but it took a lot of hacking around to make this work on Debian/Ubuntu!
Now before you ask why bother running wine and python, the reason is because Python executables are NOT cross-platform. If you run pyinstaller in Linux, that binary will only run on Linux and the same if you do it in Windows. So it is preferable if you have a single environment that you can create Linux and Windows binaries from rather than running 2 separate........