It looks like this has something to do with APIC but I am not sure. I have similar CPUs with a different MB and BIOS that work fine on the same type of kernel. A lot of time the issue is because of the C-step setting in the BIOS.
The same thing happened on the 2.6 kernel with Centos 6 but this is a homebrew 4.4 kernel soI am not sure why it is happening when even Centos 7 (3.2) kernel works OK.
Solution - It comes down to the BIOS set........
This is obviously a bug in the r8169 kernel module and it seems to affect a lot of people. I upgraded to the latest kernel and hope this won't happen anymore, as it is a very serious error. This is especially serious for those who are running servers with this chipset, who can afford for the NIC to randomly go off-line for no apparent reason?
[655548.189113] type=1505 audit(1277067560.902:5): operation="profile_load" name="/usr/bin/freshclam&q........