This is often the result of PayPal's "item name" or another name having invalid characters or not supporting Unicode.
22.214.171.124 - - [17/Jul/2018:13:39:45 -0400] "POST //modules/gateways/callback/paypal.php HTTP/1.1" 406 - "-" "PayPal IPN ( https://www.paypal.com/ipn )"
A good clue is if you check the debug output of the IPN and find a mandatory column empty.
Obviously item_name has to be populated or things will usually break. Login to your PayPal settings and update your character encoding settings:
See how to do this in PayPal below:
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